Published: Fri, 07 Mar 2014 15:02:22 GMT
The progression of Alzheimer's may slow once symptoms appear and do significant damage, according to a study investigating an inherited form of the disease. Through an international study, researchers have found rapid neuronal damage begins 10 to 20 years before symptoms appear. The next part of the study involves a clinical trial using a range of imaging techniques, and analysis of blood and cerebrospinal fluid, as participants trial new drugs to test their safety, side effects and changes within the brain.
Published: Fri, 07 Mar 2014 13:37:04 GMT
Exposure to high levels of traffic-related air pollution is associated with changes in the right ventricle of the heart that may contribute to the known connection between air pollution exposure and heart disease, according to a new study. “The morphologic changes in the right ventricle of the heart that we found with increased exposure to nitrogen dioxide add to the body of evidence supporting a connection between traffic-related air pollution and cardiovascular disease,” said the lead author. “The many adverse effects of air pollution on human health support continued efforts to reduce this burden.”
Published: Fri, 07 Mar 2014 02:10:34 GMT
Determining MRI RF heating safety is a complex process that requires complete understanding of the potential interactions between the MRI system, lead behavior, and individual patient characteristics. A comprehensive analysis was performed to evaluate a new MR-compatible SCS lead.
Published: Thu, 06 Mar 2014 14:52:59 GMT
Scientists have demonstrated for the first time worldwide that 7-Tesla ultra-high-field magnetic resonance imaging (MRI) can be used for clinical applications in patients with breast tumors. This may in future facilitate even more accurate diagnosis of breast cancer.
Published: Wed, 05 Mar 2014 13:48:42 GMT
Ultra-high-field magnetic resonance imaging (MRI) provides detailed views of a brain area implicated in Parkinson's disease, possibly leading to earlier detection of a condition that affects millions worldwide. Parkinson's disease is a chronic, progressive disease characterized by shaking, stiffness, and impaired balance and coordination. With no radiologic techniques available to aid in diagnosis, clinicians have had to rely on medical history and neurological examination. It is often difficult to distinguish Parkinson's disease from other conditions using these methods alone.
Published: Tue, 04 Mar 2014 17:59:33 GMT
Computer simulations have been developed for aircraft design to improve treatment of human airways. Computational Fluid Dynamics, or CFD, uses computer algorithms to solve the flow of air or fluids for various applications. These algorithms are typically applied toward the design of aircraft. While designing an aircraft, CFD is often considered both an accurate and less expensive approach before investing in building models and testing in air tunnels. But over the past decade or so, the application of CFD to biological flows to study medically-related problems, including respiratory disorders has gained a great deal of interest. The computer simulations traditionally used for aircraft design found use in treating health conditions such as cystic fibrosis, asthma, sleep apnea and snoring.
Published: Tue, 04 Mar 2014 12:15:25 GMT
Noninvasive imaging of carotid artery plaque with MRI can accurately predict future cardiovascular events like strokes and heart attacks in people without a history of cardiovascular disease, according to a new study. Researchers have long known that some arterial plaque is more dangerous because of its vulnerability to rupture. MRI can discern features of vulnerable plaque, such as a lipid core with a thin fibrous cap. This ability makes MRI a potentially valuable tool for identifying patients at risk for subsequent cardiovascular events.
Published: Tue, 04 Mar 2014 02:12:55 GMT
Veterans exposed to explosions who do not report symptoms of traumatic brain injury (TBI) may still have damage to the brain's white matter comparable to veterans with TBI, according to researchers. Veterans of recent military conflicts in Iraq and Afghanistan often have a history of exposure to explosive forces from bombs, grenades and other devices, although relatively little is known about whether this injures the brain. However, evidence is building – particularly among professional athletes – that subconcussive events have an effect on the brain.
Published: Mon, 03 Mar 2014 13:35:55 GMT
There are many reasons why in the era of cutting-edge medicine it is still difficult to cure cancer. A tumor may, for instance, consist of different tumor cell subpopulations, each of which has its own profile and responds differently to therapy – or not. Furthermore, the cancer cells and the healthy cells in the body interact and communicate with one another. How a tumor then actually develops and whether metastases form depends on which signals a tumor cell receives from its environment. With the development of a new method a team of reserachers has succeeded in comprehensively profiling and visualizing tumor cells from patient samples.
Published: Mon, 03 Mar 2014 13:35:49 GMT
The first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual’s potential risk for Parkinson’s disease has been developed by scientists. The probe can detect with high precision the activity of Monoamine Oxidase B (MAO-B), an enzyme that is found in elevated levels in patients with Parkinson’s disease. This innovation paves the way for the development of less costly non-invasive technologies and devices to help monitor the risk and progression of Parkinson’s disease.