Published: Fri, 31 Jul 2015 11:04:56 GMT
Researchers have gained new insight into the phases of breast cancer growth. The ability to visualize and characterize the composition of a tumor in detail during its development can provide valuable insights in order to target appropriate therapeutics.
Published: Thu, 30 Jul 2015 12:14:05 GMT
Patients undergoing surgery for lung cancer may wait too long to receive treatment, and too many patients skip vital diagnostic steps that are needed to help determine the best possible treatment, researchers report.
Published: Wed, 29 Jul 2015 18:24:22 GMT
New molecular tools are emerging to identify lung adenocarcinomas during pulmonary resection. The results of a proof-of-concept study suggest that lung cancer fluorescent imaging during surgery using targeted molecular agents may soon be a reality. While the methodology still needs refinement, the technique holds the possibility of precise visualization of tumor margins, detection of other tumors or metastases, localization of small malignant ground glass opacities, and accurate identification of lymph nodes containing metastatic cancer cells.
Published: Wed, 29 Jul 2015 18:19:13 GMT
An endoscopic probe that delivers adjustable-focus capabilities in a slimmer package has been developed by researchers. The findings could ultimately facilitate more effective and less painful imaging of internal tissues.
Published: Wed, 29 Jul 2015 15:38:46 GMT
An organic dye that can light up cancer cells for two powerful imaging techniques providing complementary diagnostic information has been developed and successfully tested in mice, researchers report.
Published: Tue, 28 Jul 2015 16:03:59 GMT
Researchers are looking for biomarkers that might serve as an early warning system for Alzheimer's disease. The process is not without complications, but these scientists possess a collective “Rosie the Riveter” spirit.
Published: Tue, 28 Jul 2015 13:17:23 GMT
Diseases like Alzheimer's are caused when proteins aggregate and clump together. In a world first, scientists have successfully distinguished between the disease-causing aggregation forms of proteins. The finding can help change pharmaceutical treatment of neurodegenerative diseases.
Published: Tue, 28 Jul 2015 13:17:18 GMT
Specific cardiovascular risk factors, such as alcohol consumption, smoking, obesity and diabetes, are associated with smaller regional brain volumes that may be early indicators of Alzheimer's disease and dementia according to a study.
Published: Mon, 27 Jul 2015 19:37:31 GMT
A new technique that could help surgeons more precisely define the locations of pituitary tumors in near real-time has been demonstrated by a team of scientists. The new strategy uses a visualization technique (matrix-assisted laser desorption/ionization mass spectrometry imaging -- MALDI MSI) that can analyze specific hormones, including growth hormone and prolactin, in tissue.
Published: Wed, 22 Jul 2015 20:42:33 GMT
Scientists found two previously overlooked clues in the health records of 131 children and teens with chest masses. Patients with enlarged lymph nodes in the neck and low levels of certain white blood cells were more likely to have cancer. Masses located in front of the heart were also more likely to be malignant, they report.
Published: Wed, 22 Jul 2015 18:46:34 GMT
Using new laboratory technology, scientists have shown that cellular damage is detectable in patients after CT scanning. In this study, researchers examined the effects on human cells of low-dose radiation from a wide range of cardiac and vascular CT scans. These imaging procedures are commonly used for a number of reasons, including management of patients suspected of having obstructive coronary artery disease, and for those with aortic stenosis, in preparation of transcatheter aortic valve replacement.
Published: Tue, 21 Jul 2015 16:50:18 GMT
The capture and analysis of circulating tumor cells (CTCs) is a valuable tool for cancer treatment decisions and therapy monitoring. Researchers are using sound waves to isolate CTCs without physical contact or damage to the cells, assuring that their original characteristics are maintained. The contact-free nature of the method offers the potential for more precise cancer treatment and monitoring.
Published: Tue, 21 Jul 2015 12:15:09 GMT
Clinical examinations and magnetic resonance imaging studies have determined whether retired professional rugby players experience more serious symptoms of cervical spine degeneration than people in the general population. To the best of the authors' knowledge, this is the largest study of its kind covering any professional contact sport, and it confirms greater cervical spine degeneration in former rugby players.
Published: Mon, 20 Jul 2015 21:58:15 GMT
Examining post-mortem tissue from the brains of people with Alzheimer's disease, investigators identified what appear to be iron-containing microglia in a particular part of the hippocampus, a key brain structure whose integrity is critical to memory formation.
Published: Mon, 20 Jul 2015 18:53:25 GMT
Scientists have, for the first time, demonstrated the importance of sodium-dependent glucose transporters (SGLTs) in delivering glucose to pancreatic and prostate cancer cells. Their study results show promising evidence that current SGLT inhibitor drugs (such as those commonly used to treat diabetes) could potentially be used to block glucose uptake and reduce tumor growth in these cancers. The researchers also utilized PET imaging to measure SGLT activity, suggesting the technology could be used to better diagnose pancreatic and prostate cancers. Pancreatic and prostate cancers are among the most deadly forms of cancer in men, and new therapies are urgently needed to combat these diseases.
Published: Sat, 18 Jul 2015 03:07:55 GMT
A new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance has been described by researchers. The team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.
Published: Thu, 16 Jul 2015 20:11:20 GMT
Polymer nanoparticles that release medicine at controlled rates inside cells have the potential to enhance the efficacy of many clinical drugs. Researchers have now developed an eye-catching way to evaluate the performance of different polymer drug-delivery formulations using luminescent quantum dots as imaging labels.
Published: Thu, 16 Jul 2015 16:44:51 GMT
Researchers demonstrate unprecedented multispectral microscope, capable of processing nearly 17 billion pixels, the largest such microscopic image ever created, to advance drug research.
Published: Thu, 16 Jul 2015 13:15:28 GMT
By analyzing blood flow in the brain, a team of researchers was able to observe the interactions between different regions in the brain in real time. Their new imaging technique could help with the early detection of Alzheimer's disease.
Published: Wed, 15 Jul 2015 16:23:59 GMT
Final results of the randomized intergroup EORTC, LYSA (Lymphoma Study Association), FIL (Fondazione Italiana Linfomi) H10 trial show that early FDG-PET ( 2-deoxy-2[F-18]fluoro-D-glucose positron emission tomography) adapted treatment improves the outcome of early FDG-PET-positive patients with stages I/II Hodgkin lymphoma.